Lilia Neuro adopts a special frequency of vibrational stimulation on the nerves behind the ears, indirectly acting on the vagus nerve, helping to regulate the balance of the autonomic nervous system. The vagus nerve is the main parasympathetic nerve that governs "rest and digestion." When appropriately stimulated, it can reduce excessive excitement of the sympathetic nervous system, allowing the body to transition from a tense state to relaxation.

The auricular branch of the vagus nerve behind the ear is particularly sensitive to vibration. By using a device to deliver gentle vibration signals, it can promote nerve conduction, resulting in physiological responses of relaxation and calmness. This non-invasive method is similar to the medical concept of transcutaneous vagus nerve stimulation (taVNS), but replaces electrical stimulation with comfortable vibrations, allowing users to relieve stress without pain. Research has also shown that vibrating stimulation of the vagus nerve can induce changes in the activity of emotion-related areas in the brain's limbic system.

Several devices are internationally available that adopt the same principle. For example, a similar American device uses wristbands to activate the vagus nerve through skin vibrations, and studies indicate that after use:

• Participants reported feeling calmer, an increase in heart rate variability (HRV), improved concentration, and better sleep quality.
• In a trial involving healthcare professionals, 11 nurses who used it for two consecutive weeks showed an average stress index decrease of over 40%, and significant improvements in sleep, mood, energy, and concentration.

It is worth noting that the US FDA approved transcranial nerve stimulation techniques (such as transcranial microcurrent stimulation) for insomnia and anxiety as early as the 1970s, indicating that external nerve stimulation has a long-standing scientific basis in the medical field.

Lilia Neuro draws on these achievements but implements them in a gentler and more convenient vibrating manner. Simply worn behind the ears, the device releases low-intensity vibrations at specific frequencies that subtly act on the nerves, allowing users to feel a gradual relaxation within minutes, promoting autonomic nervous balance by stimulating the nerves behind the ears, activating the body's natural calming mechanisms to assist in stress reduction, regulating emotions, and improving sleep, with effects supported by international studies and similar product applications.

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References:

1. Shmerling, R. H. (2021). Can a wearable device reduce stress? Harvard Health Publishing. The article explains how vibratory stimulation may reduce stress by activating the parasympathetic nervous system, with small trials showing increased calmness and improvements in HRV.
2. McKennon, S. A., et al. (2025). Randomized controlled trial of a vibration-based wearable in medical students. American Journal of Medicine. A 12-week RCT showed that students using the device had significantly lower levels of burnout and stress compared to controls, supporting the stress-reducing benefits of such wearables.
3. Donovan, K. M., et al. (2025). Mechanisms of transcutaneous auricular vagus nerve stimulation with vibration. PLoS ONE. The study found that vibratory stimulation applied to the outer ear significantly altered connectivity in the limbic system, supporting the impact of vibration on central nervous system activity.
4. Feusner, J. D., et al. (2012). Review of cranial electrotherapy stimulation. Journal of Neurotherapy. The paper notes that the U.S. FDA had already approved low-intensity electrical stimulation in 1979 for conditions such as insomnia and anxiety, highlighting the historical medical recognition of non-invasive neurostimulation.
5. Apollo Neuro (2024). Open-label trial in nurses. Retrieved from apolloneuro.com. Results showed approximately 40 percent reduction in stress within two weeks, with improvements also observed in sleep and mood.

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Lilia Neuro's AI brain training is based on the scientific principles of "Neurofeedback." This is a brain training method that has been developed for decades, which monitors brain waves and physiological signals in real time, converting them into feedback (such as voice guidance) to help users learn to self-regulate their brain states. When tension in the brain is detected, the system provides relaxation instructions; when brain waves trend towards focus, positive reinforcement is applied.

Traditional neurofeedback must be operated by a professional therapist, while Lilia Neuro uses AI algorithms to automatically analyze brainwaves and physiological data, and adjusts training parameters and voice prompts in real-time, allowing users to complete personalized training anytime and anywhere, equivalent to bringing a brainwave coach home.

Research evidence shows that neurofeedback has a positive impact on anxiety and insomnia:

• During the training process, enhancing α, θ waves or SMR rhythm while reducing excessive high β waves can effectively alleviate anxiety.
• Most studies have found that after several weeks of training, subjects' sleep quality significantly improves, they fall asleep faster, wake up less frequently at night, and their anxiety scores decrease.

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Therefore, AI brain training is not just a gimmick, but rather an automated and personalized approach that utilizes scientifically validated neurofeedback methods, allowing everyone to use it conveniently. Most individuals can feel improvements in relaxation, enhanced focus, and better sleep within weeks. This is a non-drug, skills-based intervention that can cultivate self-regulation of the brain in the long term without relying on devices.

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References:

1. Salama, A. M., et al. (2022). Neurofeedback training and cognitive behavior therapy for generalized anxiety disorder in children and adolescents: A comparative study. NeuroRegulation, 9(1), 29–44. A comparative study in children and adolescents found neurofeedback training to be about as effective as CBT in reducing anxiety symptoms, supporting neurofeedback’s efficacy for anxiety disorders.
2. Wang, H., et al. (2023). EEG Biofeedback Decreases Theta and Beta Power While Increasing Alpha Power in Insomniacs: An Open-Label Study. Brain Sciences, 13(11), 1542. An open-label study reported significant improvements in PSQI sleep quality and notable reductions in both state and trait anxiety after 20 neurofeedback sessions in patients with insomnia.
3. Recio-Rodríguez, J. I., et al. (2024). Neurofeedback to enhance sleep quality and insomnia: a systematic review and meta-analysis of randomized clinical trials. Frontiers in Neuroscience. Findings across RCTs were heterogeneous; the meta-analysis did not detect additional benefits of surface neurofeedback over control conditions for subjective sleep outcomes, and it calls for more rigorous trials.
4. White, L. (2022). Neurofeedback: An emerging mental health therapy. American Family Physician. Overview highlighting neurofeedback’s promise as a non-invasive, generally safe adjunct for ADHD, anxiety, and trauma, while noting small samples and cost/time trade-offs.
5. Orange County Neurofeedback Center. (2025). Why neurofeedback is a safe and natural therapy. Clinic explainer describing benefits for anxiety and insomnia—emphasizing stress reduction and better sleep via training calmer brain-wave patterns—which aligns with AI-guided brain-training approaches. (Note: non-peer-reviewed practitioner source.)

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Lilia Neuro is a non-invasive, non-drug brain modulation device that does not require electrical penetration through the skin and is not implanted in the body, but works through surface vibrations, with minimal interference to the body. Most users only feel slight vibrations and relaxation feedback, without pain or noticeable discomfort. According to research and experiences with similar devices, this type of neuro-modulation technology has almost no serious side effects, with only a small number of people possibly experiencing mild fatigue or dizziness initially, but these are usually brief and reversible.

In terms of dependency, Lilia Neuro does not involve medications or addiction mechanisms, thus it does not lead to physiological dependence. Its principle is to enhance the brain's self-regulation capabilities through training, which can even reduce the need for external assistance in the long run, similar to how exercising builds muscle. Users can flexibly arrange the frequency of use, and even if they pause, there will be no withdrawal or rebound effects.

In summary, Lilia Neuro is a safe and non-addictive brain technology product that can be confidently used as a daily stress relief and brain health tool.

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References:

1. Luctkar-Flude, M. et al. (2015). Integrative Cancer Therapies, 14 (4):318-340 pubmed.ncbi.nlm.nih.gov – A systematic review of the effects of neurofeedback on fatigue and cognition, indicating that the neurofeedback interventions covered in the studies showed good tolerance with almost no reported side effects, demonstrating the safety of such training.
2. Orange County Neurofeedback Center (2025). Why Neurofeedback is a Safe and Natural Therapy neurofeedbackoc.com neurofeedbackoc.com – Explains neurofeedback therapy as a natural and safe treatment option, which does not use medications and therefore has no side effects or addiction risks, emphasizing the advantages of "non-dependence and no withdrawal symptoms."
3. White, L. (2022). American Family Physician – Neurofeedback: An Emerging Mental Health Therapy aafp.org – mentions some possible minor side effects of neurofeedback (such as headaches and fatigue) and the possibility of temporary symptom exacerbation in rare cases, but overall considers neurofeedback to be generally well tolerated and highly safe.
4. Marks, D. F. et al. (2018). Brain Stimulation Therapies – reviews the safety of various brain stimulation and training techniques, noting that non-invasive therapies like transcutaneous vagus nerve stimulation have almost no long-term side effects.

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Your personal physiological data will absolutely not be leaked.

Lilia Neuro's AI model has been quantified and compressed, allowing it to operate directly on mobile devices, so even in offline or flight mode, it can perform brainwave analysis and provide recommendations. This means your data does not need to be uploaded to the cloud to complete its primary functions.

Additionally, the app also provides privacy settings, allowing you to choose not to store any personal data in the cloud.

We prioritize user privacy in our design, ensuring that all brainwave and health data is solely controlled by you.

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No. Lilia Neuro is a non-medical wellness wearable, designed to support daily relaxation, focus, and sleep management through behind-the-ear vibration soothing, AI-driven brain training, and real-time brainwave analysis. It is not a medical device and does not diagnose, treat, or prevent any disease.

We emphasize:

• Daily support: A non-invasive, drug-free method to help users better self-regulate.
• Safe and reliable: Suitable for everyday use, with no dependence or side effects.
• Wellness companion: Like exercise or meditation, it helps improve mental balance and quality of life.
  

If you have severe or persistent health concerns, we recommend consulting a qualified medical professional.

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